Alzheimer's disease.
Vascular dementia.
Dementia with Lewy bodies.
Adult/Elderly: Initial 5 mg once daily. Maximum dose: 10 mg per day. May be increased to 10 mg/day after at least 4-6 weeks of clinical assessment in patients who tolerated treatment at 5 mg/day.
Hypersensitivity to donepezil hydrochloride or piperidine derivatives.
May exaggerate succinylcholine-type muscle relaxation during anesthesia. Patients with sick-sinus syndrome, supraventricular cardiac conduction conditions eg, SA or AV block, history of ulcer disease or those receiving concurrent NSAIDs; history of asthma or obstructive pulmonary disease. May exacerbate or induce extrapyramidal symptoms; cause bladder outflow obstruction. Avoid concomitant use with inhibitors of acetylcholinesterase, agonists or antagonists of the cholinergic system. Severe hepatic impairment. May affect ability to drive or operate machinery.
Use in Pregnancy & Lactation: Caution for pregnancy & lactation.
Use in Children: Not recommended for children.
Caution for pregnancy & lactation.
Diarrhoea, nausea; headache. Common cold; anorexia; hallucinations, agitation, aggressive behaviour; syncope, dizziness, insomnia; vomiting, abdominal disturbance; rash, pruritis; muscle cramps; urinary incontinence; fatigue, pain; accident.
CYP3A4 and CYP2D6 inhibitors may inhibit donepezil metabolism. Reduced levels with rifampicin, phenytoin, carbamazepine. May interfere with drugs having anticholinergic activity. Concomitant use with succinylcholine, other neuromuscular and β-blocking agents, & cholinergic agonists may produce synergistic activity on cardiac conduction.
N06DA02 - donepezil ; Belongs to the class of anticholinesterases. Used in the management of dementia.
Ceptia 10 orodispersible tab 10 mg
3 × 10's
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